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1

Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes

Perera, Dilmi, Poulos, Rebecca C., Shah, Anushi, Beck, Dominik, Pimanda, John E., Wong, Jason W. H.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.40 MB

english, 2016

2

RNA splicing alterations induce a cellular stress response associated with poor prognosis in Acute Myeloid Leukemia

Anande, Govardhan, Deshpande, Nandan P., Mareschal, Sylvain, Batcha, Aarif M.N., Hampton, Henry R., Herold, Tobias, Lehmann, SÃ¶ren, Wilkins, Marc R, Wong, Jason W. H., Unnikrishnan, Ashwin, Pimanda,

Journal:

Clinical Cancer Research

Year:

2020

File:

PDF, 7.09 MB

2020

3

Control of von Willebrand factor multimer size and implications for disease

John Pimanda, Philip Hogg

Journal:

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

4

Concise Review: Blood Relatives: Formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1

David J. Curtis, Jessica M. Salmon, John E. Pimanda

Journal:

Year:

2012

Language:

english

File:

PDF, 902 KB

english, 2012

5

Pdgfrα and Flk1 are direct target genes of Mixl1 in differentiating embryonic stem cells

Lloyd A. Pereira, Michael S. Wong, Anna K. Mossman, Koula Sourris, Mary E. Janes, Kathy Knezevic, Claire E. Hirst, Sue Mei Lim, John E. Pimanda, Edouard G. Stanley, Andrew G. Elefanty

Journal:

Stem Cell Research

Year:

2012

Language:

english

File:

PDF, 1.96 MB

english, 2012

6

A perspective on the measurement of ADAMTS13 in thrombotic thrombocytopaenic purpura

John E. Pimanda, Colin N. Chesterman, Philip J. Hogg

Journal:

European Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 110 KB

english, 2003

7

Genome-wide computational screen for bloon stem cell enhancers integrates RUNX1 and the BMP signaling pathway into the SCL transcriptional network

John E. Pimanda, Ian J. Donaldson, Marella F.T.R. de Bruijn, Sarah Kinston, Kathy Knezevic, Liz Huckle, Sandie Piltz, Josette-Renée Landry, Anthony R. Green, David Tannahill, Berthold Göttgens

Journal:

Blood Cells, Molecules, and Diseases

Year:

2007

Language:

english

File:

PDF, 67 KB

english, 2007

8

Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators

Nicola K. Wilson, Samuel D. Foster, Xiaonan Wang, Kathy Knezevic, Judith Schütte, Polynikis Kaimakis, Paulina M. Chilarska, Sarah Kinston, Willem H. Ouwehand, Elaine Dzierzak, John E. Pimanda, Marella

Journal:

Year:

2010

Language:

english

File:

PDF, 1.40 MB

english, 2010

9

Cell signalling pathways that mediate haematopoietic stem cell specification

Marks-Bluth, Jonathon, Pimanda, John E.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2012

Language:

english

File:

PDF, 695 KB

english, 2012

10

Mathematical model of a gene regulatory network reconciles effects of genetic perturbations on hematopoietic stem cell emergence

Narula, Jatin, Williams, C.J., Tiwari, Abhinav, Marks-Bluth, Jonathon, Pimanda, John E., Igoshin, Oleg A.

Journal:

Developmental Biology

Year:

2013

Language:

english

File:

PDF, 835 KB

english, 2013

11

Enriching hemangioblast and hemogenic endothelial cells using regulatory elements of the endoglin gene

Nasrallah, Rabab, Knezevic, Kathy, Janes, Mary, Smith, Aileen, Gottgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Pimanda, John

Journal:

Experimental Hematology

Year:

2013

Language:

english

File:

PDF, 44 KB

english, 2013

12

Genome-wide analysis of transcriptional regulators in human hscs reveals a densely interconnected network of coding and non-coding genes

Beck, Dominik, Thoms, Julie, Perera, Dilmi, Unnikrishnan, Ashwin, Knezevic, Kathy, O'Brien, Tracey, Gottgens, Berthold, Wong, Jason, Pimanda, John

Journal:

Experimental Hematology

Year:

2013

Language:

english

File:

PDF, 47 KB

english, 2013

13

Endoglin modulates stage specific cell responses during lineage commitment from embryonic stem cells to blood and endothelium

Nasrallah, Rabab, Knezevic, Kathy, Gottgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Pimanda, John

Journal:

Experimental Hematology

Year:

2014

Language:

english

File:

PDF, 52 KB

english, 2014

14

Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells

Khanna, A., Kauko, O., Bockelman, C., Laine, A., Schreck, I., Partanen, J. I., Szwajda, A., Bormann, S., Bilgen, T., Helenius, M., Pokharel, Y. R., Pimanda, J., Russel, M. R., Haglund, C., Cole, K. A.

Journal:

Cancer Research

Year:

2013

Language:

english

File:

PDF, 2.09 MB

english, 2013

15

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

Beck, D., Thoms, J. A. I., Perera, D., Schutte, J., Unnikrishnan, A., Knezevic, K., Kinston, S. J., Wilson, N. K., O'Brien, T. A., Gottgens, B., Wong, J. W. H., Pimanda, J. E.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.79 MB

english, 2013

16

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

Taoudi, S., Bee, T., Hilton, A., Knezevic, K., Scott, J., Willson, T. A., Collin, C., Thomas, T., Voss, A. K., Kile, B. T., Alexander, W. S., Pimanda, J. E., Hilton, D. J.

Journal:

Genes & Development

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

17

Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia

Oram, S H, Thoms, J, Sive, J I, Calero-Nieto, F J, Kinston, S J, Schütte, J, Knezevic, K, Lock, R B, Pimanda, J E, Göttgens, B

Journal:

Year:

2013

Language:

english

File:

PDF, 1.90 MB

english, 2013

18

Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia

Sloane, Mathew A, Wong, Jason WH, Perera, Dilmi, Nunez, Andrea C, Pimanda, John E, Hawkins, Nicholas J, Sieber, Oliver M, Bourke, Michael J, Hesson, Luke B, Ward, Robyn L

Journal:

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

19

OncoCis: annotation ofcis-regulatory mutations in cancer

Perera, Dilmi, Chacon, Diego, Thoms, Julie AI, Poulos, Rebecca C, Shlien, Adam, Beck, Dominik, Campbell, Peter J, Pimanda, John E, Wong, Jason WH

Journal:

Year:

2014

Language:

english

File:

PDF, 3.08 MB

english, 2014

20

BloodChIP: a database of comparative genome-wide transcription factor binding profiles in human blood cells

Chacon, D., Beck, D., Perera, D., Wong, J. W. H., Pimanda, J. E.

Journal:

Nucleic Acids Research

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

21

Cancerous Inhibitor of Protein Phosphatase 2A, an Emerging Human Oncoprotein and a Potential Cancer Therapy Target

Khanna, A., Pimanda, J. E., Westermarck, J.

Journal:

Cancer Research

Year:

2013

Language:

english

File:

PDF, 353 KB

english, 2013

22

Phosphorylation and Acetylation of Histone H3 and Autoregulation by Early Growth Response 1 Mediate Interleukin 1 Induction of Early Growth Response 1 Transcription

Wang, B., Chen, J., Santiago, F. S., Janes, M., Kavurma, M. M., Chong, B. H., Pimanda, J. E., Khachigian, L. M.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2010

Language:

english

File:

PDF, 777 KB

english, 2010

23

72 PERSONALIZED TREATMENT APPROACH FOR GFI136N HETEROZYGOUS OR HOMOZYGOUS MDS PATIENTS

Lacramioara, B., Makishima, H., Michel, L., Hoenes, J., Marneth, A., van der Reijden, B., Radiovoyevich, T., Germing, U., Haas, R., Schroeder, T., Vadnais, C., Helness, A., Pimanda, J., Jansen, J., Un

Journal:

Leukemia Research

Year:

2015

Language:

english

File:

PDF, 61 KB

english, 2015

24

The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity

Pimanda, John E., Donaldson, Ian J., de Bruijn, Marella F. T. R., Kinston, Sarah, Knezevic, Kathy, Huckle, Liz, Piltz, Sandie, Landry, Josette-Renée, Green, Anthony R., Tannahill, David, Göttgens, Ber

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 2.99 MB

english, 2007

25

Relative Distribution of Folate Species Is Associated with Global DNA Methylation in Human Colorectal Mucosa

Liu, J., Hesson, L. B., Meagher, A. P., Bourke, M. J., Hawkins, N. J., Rand, K. N., Molloy, P. L., Pimanda, J. E., Ward, R. L.

Journal:

Cancer Prevention Research

Year:

2012

Language:

english

File:

PDF, 740 KB

english, 2012

26

Clinical significance of cancerous inhibitor of protein phosphatase 2A in human cancers

Khanna, Anchit, Pimanda, John E.

Journal:

International Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 445 KB

english, 2015

27

Role of Thrombospondin-1 in Control of von Willebrand Factor Multimer Size in Mice

Pimanda, J. E., Ganderton, T., Maekawa, A., Yap, C. L., Lawler, J., Kershaw, G., Chesterman, C. N., Hogg, P. J.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1.17 MB

english, 2004

28

Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

Nasrallah, R., Knezevic, K., Thai, T., Thomas, S. R., Gottgens, B., Lacaud, G., Kouskoff, V., Pimanda, J. E.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

29

A Runx1-Smad6 Rheostat Controls Runx1 Activity during Embryonic Hematopoiesis

Knezevic, K., Bee, T., Wilson, N. K., Janes, M. E., Kinston, S., Polderdijk, S., Kolb-Kokocinski, A., Ottersbach, K., Pencovich, N., Groner, Y., de Bruijn, M., Gottgens, B., Pimanda, J. E.

Journal:

Molecular and Cellular Biology

Year:

2011

Language:

english

File:

PDF, 133 KB

english, 2011

30

Reassembly of Nucleosomes at the MLH1 Promoter Initiates Resilencing Following Decitabine Exposure

Hesson, Luke B., Patil, Vibha, Sloane, Mathew A., Nunez, Andrea C., Liu, Jia, Pimanda, John E., Ward, Robyn L., Horwitz, Marshall S.

Journal:

Year:

2013

Language:

english

File:

PDF, 988 KB

english, 2013

31

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

Pimanda, J. E., Ottersbach, K., Knezevic, K., Kinston, S., Chan, W. Y. I., Wilson, N. K., Landry, J.-R., Wood, A. D., Kolb-Kokocinski, A., Green, A. R., Tannahill, D., Lacaud, G., Kouskoff, V., Gottge

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 1.03 MB

english, 2007

32

Systematic Screening of Promoter Regions Pinpoints Functional Cis-regulatory Mutations in a Cutaneous Melanoma Genome

Poulos, R. C., Thoms, J. A. I., Shah, A., Beck, D., Pimanda, J. E., Wong, J. W. H.

Journal:

Molecular Cancer Research

Year:

2015

Language:

english

File:

PDF, 1.51 MB

english, 2015

33

Transcriptional Link between Blood and Bone: the Stem Cell Leukemia Gene and Its +19 Stem Cell Enhancer Are Active in Bone Cells

Pimanda, J. E., Silberstein, L., Dominici, M., Dekel, B., Bowen, M., Oldham, S., Kallianpur, A., Brandt, S. J., Tannahill, D., Gottgens, B., Green, A. R.

Journal:

Molecular and Cellular Biology

Year:

2006

Language:

english

File:

PDF, 1.33 MB

english, 2006

34

A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression

Giotopoulos, G., van der Weyden, L., Osaki, H., Rust, A. G., Gallipoli, P., Meduri, E., Horton, S. J., Chan, W.-I., Foster, D., Prinjha, R. K., Pimanda, J. E., Tenen, D. G., Vassiliou, G. S., Koschmie

Journal:

Journal of Experimental Medicine

Year:

2015

Language:

english

File:

PDF, 4.36 MB

english, 2015

35

Characteristics of stromal stem cells in the foetal liver

Qiao, Qiao, Chandrakanthan, Vashe, Pimanda, John

Journal:

Experimental Hematology

Year:

2015

Language:

english

File:

PDF, 46 KB

english, 2015

36

Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a

Shields, Benjamin J., Jackson, Jacob T., Metcalf, Donald, Shi, Wei, Huang, Qiutong, Garnham, Alexandra L., Glaser, Stefan P., Beck, Dominik, Pimanda, John E., Bogue, Clifford W., Smyth, Gordon K., Ale

Journal:

Genes & Development

Year:

2016

Language:

english

File:

PDF, 1.79 MB

english, 2016

37

117PDClinical relevance of DNA damage modulator checkpoint kinase 1 (CHK1) and cancerous inhibitor of protein phosphatase 2A (CIP2A) in human gliomas

Khanna, A., Stringer, B., Ensbey, K., Jahaan, Z., Boyd, A., McDonald, K., Day, B., Pimanda, J.

Journal:

Annals of Oncology

Year:

2015

File:

PDF, 30 KB

2015

38

117PDClinical relevance of DNA damage modulator checkpoint kinase 1 (CHK1) and cancerous inhibitor of protein phosphatase 2A (CIP2A) in human gliomas

Khanna, A., Stringer, B., Ensbey, K., Jahaan, Z., Boyd, A., McDonald, K., Day, B., Pimanda, J.

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 30 KB

english, 2015

39

Genetic fate mapping of mesenchymal stem-like cells in the aorta-gonad mesonephros (AGM) and their contribution to developmental hematopoiesis

Chandrakanthan, Vashe, Knezevic, Kathy, Kang, Young C., Qiao, Qiao, Pimanda, John

Journal:

Experimental Hematology

Year:

2015

Language:

english

File:

PDF, 45 KB

english, 2015

40

Acute sensitivity of Ph-like acute lymphoblastic leukemia to the SMAC-mimetic birinapant

Richmond, J., Robbins, A., Evans, K., Beck, D., Kurmasheva, R. T., Billups, C. A., Carol, H., Heatley, S., Sutton, R., Marshall, G. M., White, D., Pimanda, J., Houghton, P. J., Smith, M. A., Lock, R.

Journal:

Cancer Research

Year:

2016

Language:

english

File:

PDF, 13.00 MB

english, 2016

41

An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

Avellino, R., Havermans, M., Erpelinck, C., Sanders, M. A., Hoogenboezem, R., van de Werken, H. J. G., Rombouts, E., van Lom, K., van Strien, P. M. H., Gebhard, C., Rehli, M., Pimanda, J., Beck, D., E

Journal:

Year:

2016

Language:

english

File:

PDF, 3.48 MB

english, 2016

42

Integrated Genetic, Epigenetic and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumours

Hesson, L. B., Ng, B., Zarzour, P., Srivastava, S., Kwok, C.-T., Packham, D., Nunez, A. C., Beck, D., Ryan, R., Dower, A., Ford, C. E., Pimanda, J., Sloane, M. A., Hawkins, N. J., Bourke, M. J., Wong,

Journal:

Molecular Cancer Research

Year:

2016

Language:

english

File:

PDF, 2.28 MB

english, 2016

43

Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif

Poulos, Rebecca C., Thoms, Julie A.I., Guan, Yi Fang, Unnikrishnan, Ashwin, Pimanda, John E., Wong, Jason W.H.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.34 MB

english, 2016

44

Annotating Function to Differentially Expressed LincRNAs in Myelodysplastic Syndrome Using a Network-Based Method

Liu, Keqin, Beck, Dominik, Thoms, Julie A.I., Liu, Liang, Zhao, Weiling, Pimanda, John E., Zhou, Xiaobo

Journal:

Year:

2017

Language:

english

File:

PDF, 948 KB

english, 2017

45

Genetic Fate Mapping of Mesenchymal Stem-Like Cells in the Aorta-Gonad Mesonephros (AGM) and Their Contribution to Definitive Hematopoiesis

Chandrakanthan, Vashe, Kang, Young Chan, Knezevic, Kathy, Qiao, Qiao, Oliver, Rema A., Unnikrishnan, Ashwin, Beck, Dominik, Lee, Brendan, Brownlee, Chris, Power, Carl, Pimanda, John E.

Journal:

Mechanisms of Development

Year:

2017

Language:

english

File:

PDF, 66 KB

english, 2017

46

Identification of Novel Embryonic Vascular Stem-like cells and their role in Coronary Vasculature development and repair

Kang, Young Chan, Glaros, Elias, Thomas, Shane, Qiao, Qiao, Brownlee, Chris, Pimanda, John, Chandrakanthan, Vashe

Journal:

Mechanisms of Development

Year:

2017

Language:

english

File:

PDF, 61 KB

english, 2017

47

In vivo CRISPR editing of DNMT3A in JAK2V617F hematopoietic stem cells induces myelofibrosis

Jacquelin, Sebastien, Straube, Jasmin, Song, Axia, Cooper, Leanne, Vu, Therese, Heidecker, Matthew, Pimanda, John, Hesson, Luke, Hill, Geff, Cloonan, Nicole, Heckl, Dirk, Lane, Steven

Journal:

Experimental Hematology

Year:

2017

Language:

english

File:

PDF, 225 KB

english, 2017

48

The Proto-Oncogene ERG in Megakaryoblastic Leukemias

Rainis, Liat, Toki, Tsutomu, Pimanda, John E., Rosenthal, Ester, Machol, Keren, Strehl, Sabine, Göttgens, Berthold, Ito, Etsuro, Izraeli, Shai

Journal:

Cancer Research

Year:

2005

Language:

english

File:

PDF, 571 KB

english, 2005

49

Declined presentation characterisation of stromal cell populations in the foetal liver and their contributions to embryonic haematopoietic and vascular development

Chandrakanthan, Vashe, Qiao, Qiao, Chan Kang, Young, Knezevic, Kathy, Oliver, Rema, Loo, Christine, Anande, Govardhan, Lee, Brendan, Walsh, Willam, Power, Carl, Wong, Jason, Pimanda, John

Journal:

Experimental Hematology

Year:

2017

Language:

english

File:

PDF, 133 KB

english, 2017

50

Maintenance of primitive haematopoiesis is shared by SCL and LYL1

Chiu, Sung Kai, Saw, Jesslyn, Huang, Yizhou, Beck, Dominic, Powell, David, Pimanda, John, Tremblay, Cedric, Curtis, David

Journal:

Experimental Hematology

Year:

2017

Language:

english

File:

PDF, 227 KB

english, 2017

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